Specific Detection of Naturally Occurring Hepatitis C Virus Mutants with Resistance to Telaprevir and Boceprevir (Protease Inhibitors) among Treatment-Naïve Infected Individuals

The use of telaprevir and boceprevir, both protease inhibitors (PI), as part of the specifically targeted antiviral therapy for hepatitis C (STAT-C) has significantly improved sustained virologic response (SVR) rates. However, different clinical studies have also identified several mutations associa...

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Detalhes bibliográficos
Main Authors: Fonseca-Coronado, Salvador, Escobar-Gutiérrez, Alejandro, Ruiz-Tovar, Karina, Cruz-Rivera, Mayra Yolanda, Rivera-Osorio, Pilar, Vazquez-Pichardo, Mauricio, Carpio-Pedroza, Juan Carlos, Ruíz-Pacheco, Juan Alberto, Cazares, Fernando, Vaughan, Gilberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264164/
https://ncbi.nlm.nih.gov/pubmed/22116161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.05842-11
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