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Abnormal nuclear envelopes in the striatum and motor deficits in DYT11 myoclonus-dystonia mouse models

DYT11 myoclonus-dystonia (M-D) is a movement disorder characterized by myoclonic jerks with dystonic symptoms and caused by mutations in paternally expressed SGCE, which codes for ɛ-sarcoglycan. Paternally inherited Sgce heterozygous knock-out (KO) mice exhibit motor deficits and spontaneous myoclon...

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Detalles Bibliográficos
Main Authors: Yokoi, Fumiaki, Dang, Mai T., Zhou, Tong, Li, Yuqing
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263984/
https://ncbi.nlm.nih.gov/pubmed/22080833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr528
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