Methamphetamine Self-Administration Causes Persistent Striatal Dopaminergic Alterations and Mitigates the Deficits Caused by a Subsequent Methamphetamine Exposure

Preclinical studies have demonstrated that repeated methamphetamine (METH) injections (referred to herein as a “binge” treatment) cause persistent dopaminergic deficits. A few studies have also examined the persistent neurochemical impact of METH self-administration in rats, but with variable result...

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Main Authors: McFadden, Lisa M., Hadlock, Greg C., Allen, Scott C., Vieira-Brock, Paula L., Stout, Kristen A., Ellis, Jonathan D., Hoonakker, Amanda J., Andrenyak, David M., Nielsen, Shannon M., Wilkins, Diana G., Hanson, Glen R., Fleckenstein, Annette E.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2012
Fag:
Behavioral Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263961/
https://ncbi.nlm.nih.gov/pubmed/22034657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.188433
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