Circulating Brain-Derived Neurotrophic Factor Concentration Is Downregulated by Intralipid/Heparin Infusion or High-Fat Meal in Young Healthy Male Subjects

OBJECTIVE: Insulin resistance and type 2 diabetes are associated with an increased risk of neurodegenerative diseases. Brain-derived neurotrophic factor (BDNF) regulates neuronal differentiation and synaptic plasticity, and its decreased levels are supposed to play a role in the pathogenesis of Alzh...

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Hauptverfasser: Karczewska-Kupczewska, Monika, Kowalska, Irina, Nikołajuk, Agnieszka, Adamska, Agnieszka, Zielińska, Magdalena, Kamińska, Natalia, Otziomek, Elżbieta, Górska, Maria, Strczkowski, Marek
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2012
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263867/
https://ncbi.nlm.nih.gov/pubmed/22210566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc11-1295
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