Inflammatory Animal Model for Parkinson's Disease: The Intranigral Injection of LPS Induced the Inflammatory Process along with the Selective Degeneration of Nigrostriatal Dopaminergic Neurons

We have developed an animal model of degeneration of the nigrostriatal dopaminergic neurons, the neuronal system involved in Parkinson's disease (PD). The implication of neuroinflammation on this disease was originally established in 1988, when the presence of activated microglia in the substan...

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Библиографические подробности
Главные авторы: Machado, A., Herrera, A. J., Venero, J. L., Santiago, M., de Pablos, R. M., Villarán, R. F., Espinosa-Oliva, A. M., Argüelles, S., Sarmiento, M., Delgado-Cortés, M. J., Mauriño, R., Cano, J.
Формат: Artigo
Язык:Inglês
Опубликовано: International Scholarly Research Network 2011
Предметы:
Review Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263561/
https://ncbi.nlm.nih.gov/pubmed/22389821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2011/476158
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