The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network

Glioblastoma multiforme (GBM) is the most common form of primary brain tumor in adults, often characterized by poor survival. Glioma-initiating cells (GiCs) are defined by their extensive self-renewal, differentiation, and tumor initiation properties. GiCs are known to be involved in tumor growth an...

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Detalhes bibliográficos
Main Authors: Fareh, M, Turchi, L, Virolle, V, Debruyne, D, Almairac, F, de-la-Forest Divonne, S, Paquis, P, Preynat-Seauve, O, Krause, K-H, Chneiweiss, H, Virolle, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263498/
https://ncbi.nlm.nih.gov/pubmed/21720384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.89
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