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Non-Invasive Imaging of Barriers to Drug Delivery in Tumors
Solid tumors often develop high interstitial fluid pressure (IFP) as a result of increased water leakage and impaired lymphatic drainage, as well as changes in the extracellular matrix composition and elasticity. This high fluid pressure forms a barrier to drug delivery and hence, resistance to ther...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263334/ https://ncbi.nlm.nih.gov/pubmed/18638494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2008.06.002 |
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