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Efficacy of Phototherapy for Newborns with Hyperbilirubinemia: A Cautionary Example of an Instrumental Variable Analysis

BACKGROUND: Use of instrumental variables is gaining popularity as a method of controlling for confounding by indication in observational studies of treatments. OBJECTIVES: To illustrate how unmeasured instrument-level treatment substitution can distort effect size estimates using as an example an i...

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Detalhes bibliográficos
Main Authors: Newman, Thomas B., Vittinghoff, Eric, McCulloch, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263320/
https://ncbi.nlm.nih.gov/pubmed/21859678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0272989X11416512
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