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High spontaneous mutation rate of Rous sarcoma virus demonstrated by direct sequencing of the RNA genome.

Direct and extensive sequencing of RSV RNA genome is reported. More than 10,000 nt of the T1 RNase resistant RSV RNA fragments (1) have been sequenced and shown to cover 3900 nt of RSV genome. The frequent sequence variations found indicate that RSV supports a very high incidence of spontaneous muta...

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Bibliografische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Darlix, J L, Spahr, P F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1983
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6310522/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.17.5953
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