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Sequence of human haptoglobin cDNA: evidence that the alpha and beta subunits are coded by the same mRNA.

We have isolated and sequenced a cDNA clone coding for human haptoglobin. Our sequence shows that haptoglobin is very likely synthesized as a single polypeptide chain which is then cleaved at an Arg residue to generate its two characteristic alpha and beta subunit. Southern blot analysis suggests th...

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Bibliographic Details
Main Authors: Raugei, G, Bensi, G, Colantuoni, V, Romano, V, Santoro, C, Costanzo, F, Cortese, R
Format: Artigo
Language:Inglês
Published: 1983
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC326319/
https://ncbi.nlm.nih.gov/pubmed/6310515
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