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A block in lineage differentiation of immortal human mammary stem / progenitor cells by ectopically-expressed oncogenes

INTRODUCTION: Emerging evidence suggests a direct role of cancer stem cells (CSCs) in the development of breast cancer. In vitro cellular models that recapitulate properties of CSCs are therefore highly desirable. We have previously shown that normal human mammary epithelial cells (hMECs) immortaliz...

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Autors principals: Zhao, Xiangshan, Malhotra, Gautam K., Band, Hamid, Band, Vimla
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263028/
https://ncbi.nlm.nih.gov/pubmed/22279424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.91415
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