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The inhibition of the RNA polymerase activity of influenza virus A by pyrophosphate analogues.

Substituted methylene diphosphonates are effective inhibitors of the RNA polymerase of influenza A virus causing 50% inhibition of the polymerase activity when they are present in the concentration range 10-85 microM. The inhibitory power of the methylene diphosphonates appears to be related to thei...

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Detalhes bibliográficos
Main Authors: Cload, P A, Hutchinson, D W
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC326301/
https://ncbi.nlm.nih.gov/pubmed/6310507
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