Frs2α-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis

The cardiac outflow tract (OFT) is a developmentally complex structure derived from multiple lineages and is often defective in human congenital anomalies. While emerging evidence shows that the fibroblast growth factor (FGF) is essential for OFT development, the downstream pathways mediating FGF-si...

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Detalhes bibliográficos
Main Authors: Zhang, Jue, Lin, Yongshun, Zhang, Yongyou, Lan, Yongsheng, Lin, Chunhong, Moon, Anne M., Schwartz, Robert J., Martin, James F., Wang, Fen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262991/
https://ncbi.nlm.nih.gov/pubmed/18832393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.025361
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