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B–helper neutrophils stimulate immunoglobulin diversification and production in the marginal zone of the spleen

Neutrophils utilize immunoglobulins (Igs) to clear antigen, but their role in Ig production is unknown. Here we identified neutrophils around the marginal zone (MZ) of the spleen, a B cell area specialized in T-independent Ig responses to circulating antigen. Neutrophils colonized peri-MZ areas afte...

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Main Authors: Puga, Irene, Cols, Montserrat, Barra, Carolina M., He, Bing, Cassis, Linda, Gentile, Maurizio, Comerma, Laura, Chorny, Alejo, Shan, Meimei, Xu, Weifeng, Magri, Giuliana, Knowles, Daniel M., Tam, Wayne, Chiu, April, Bussel, James B, Serrano, Sergi, Lorente, José Antonio, Bellosillo, Beatriz, Lloreta, Josep, Juanpere, Nuria, Alameda, Francesc, Baró, Teresa, de Heredia, Cristina Díaz, Torán, Núria, Català, Albert, Torrebadell, Montserrat, Fortuny, Claudia, Cusi, Victoria, Carreras, Carmen, Diaz, George A., Blander, J. Magarian, Farber, Claire-Michèle, Silvestri, Guido, Cunningham-Rundles, Charlotte, Calvillo, Michaela, Dufour, Carlo, Notarangelo, Lucia Dora, Lougaris, Vassilios, Plebani, Alessandro, Casanova, Jean-Laurent, Ganal, Stephanie C., Diefenbach, Andreas, Aróstegui, Juan Ignacio, Juan, Manel, Yagüe, Jordi, Mahlaoui, Nizar, Donadieu, Jean, Chen, Kang, Cerutti, Andrea
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262910/
https://ncbi.nlm.nih.gov/pubmed/22197976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2194
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