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The 5'-flanking sequence of human interferon-beta 1 gene is responsible for viral induction of transcription.

The structural gene for Herpes simplex virus (HSV) thymidine kinase (Tk) was fused downstream of the 5'-flanking sequence (from -284 to +20; numbering relative to the putative transcription initiation site) of the cloned human interferon-beta 1 (IFN-beta 1) gene. The fusion gene was linked to t...

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Bibliografische gegevens
Hoofdauteurs: Ohno, S, Taniguchi, T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1983
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC326286/
https://ncbi.nlm.nih.gov/pubmed/6310498
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