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The 5'-flanking sequence of human interferon-beta 1 gene is responsible for viral induction of transcription.
The structural gene for Herpes simplex virus (HSV) thymidine kinase (Tk) was fused downstream of the 5'-flanking sequence (from -284 to +20; numbering relative to the putative transcription initiation site) of the cloned human interferon-beta 1 (IFN-beta 1) gene. The fusion gene was linked to t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1983
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC326286/ https://ncbi.nlm.nih.gov/pubmed/6310498 |
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