Lentiviral-Mediated RNAi Knockdown Yields a Novel Mouse Model for Studying Cyp2b Function

There are few in vivo knockout models available to study the function of Cyp2 members involved in the metabolism of endogenous and exogenous chemicals. These models may help provide insight into the cytochrome P450s (CYPs) responsible for the detoxification and activation of drugs, environmental tox...

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Detaylı Bibliyografya
Asıl Yazarlar: Damiri, Basma, Holle, Eric, Yu, Xianzhong, Baldwin, William S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Biotransformation and Toxicokinetics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262856/
https://ncbi.nlm.nih.gov/pubmed/22083726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr309
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