Over-Expression of Leptin Receptors in Hypothalamic POMC Neurons Increases Susceptibility to Diet-Induced Obesity

Diet-induced obesity (DIO) in rodents is characterized by impaired activation of signal-transducer and activator of transcription 3 (STAT3) by leptin receptors (LepRb) within the hypothalamic arcuate nucleus. This signaling defect likely plays an important role in development of DIO. However, the ne...

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Detaylı Bibliyografya
Asıl Yazarlar: Gamber, Kevin M., Huo, Lihong, Ha, Sangdeuk, Hairston, Joyce E., Greeley, Sarah, Bjørbæk, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262822/
https://ncbi.nlm.nih.gov/pubmed/22276206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030485
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