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A Novel Role for BDNF-TrkB in the Regulation of Chemotherapy Resistance in Head and Neck Squamous Cell Carcinoma

Mechanisms of resistance for HNSCC to cisplatin (CDDP), the foundational chemotherapeutic agent in the treatment of this disease, remain poorly understood. We previously demonstrated that cisplatin resistance (CR) can be overcome by targeting Trk receptor. In the current study, we explored the poten...

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Bibliografiske detaljer
Main Authors: Lee, Junegoo, Jiffar, Tilahun, Kupferman, Michael E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262811/
https://ncbi.nlm.nih.gov/pubmed/22276165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030246
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