Analysis of Marker-Defined HNSCC Subpopulations Reveals a Dynamic Regulation of Tumor Initiating Properties

Head and neck squamous carcinoma (HNSCC) tumors carry dismal long-term prognosis and the role of tumor initiating cells (TICs) in this cancer is unclear. We investigated in HNSCC xenografts whether specific tumor subpopulations contributed to tumor growth. We used a CFSE-based label retentions assay...

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Bibliografiska uppgifter
Huvudupphovsmän: Bragado, Paloma, Estrada, Yeriel, Sosa, Maria Soledad, Avivar-Valderas, Alvaro, Cannan, David, Genden, Eric, Teng, Marita, Ranganathan, Aparna C., Wen, Huei-Chi, Kapoor, Avnish, Bernstein, Emily, Aguirre-Ghiso, Julio A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262798/
https://ncbi.nlm.nih.gov/pubmed/22276135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029974
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