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Hypoxia-Inducible Factor Regulates Expression of Surfactant Protein in Alveolar Type II Cells In Vitro

Alveolar type II (ATII) cells cultured at an air–liquid (A/L) interface maintain differentiation, but they lose these properties when they are submerged. Others showed that an oxygen tension gradient develops in the culture medium as ATII cells consume oxygen. Therefore, we wondered whether hypoxia...

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Главные авторы: Ito, Yoko, Ahmad, Aftab, Kewley, Emily, Mason, Robert J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262688/
https://ncbi.nlm.nih.gov/pubmed/21454802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0052OC
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