Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin.

Fourteen mutants known or likely to contain mutations in the herpes simplex virus DNA polymerase gene were examined for their sensitivity to aphidicolin in plaque reduction assays. Eleven of these exhibited some degree of hypersensitivity to the drug; altered aphidicolin-sensitivity correlated with...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Coen, D M, Furman, P A, Aschman, D P, Schaffer, P A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1983
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326265/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6308578/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.15.5287
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