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Rewiring Integrin-Mediated Signaling and Cellular Response with the Peripheral Myelin Protein 22 and Epithelial Membrane Protein 2 Components of the Tetraspan Web

PURPOSE. Integrin-mediated collagen gel contraction by ARPE-19 is an in vitro model for proliferative vitreoretinopathy (PVR), an aberrant wound healing response after retinal detachment or ocular trauma. Expression of the tetraspan protein epithelial membrane protein 2 (EMP2) controls gel contracti...

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Главные авторы: Morales, Shawn A., Telander, David, Notterpek, Lucia, Wadehra, Madhuri, Braun, Jonathan, Gordon, Lynn K.
Формат: Artigo
Язык:Inglês
Опубликовано: Association for Research in Vision and Ophthalmology, Inc. 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262552/
https://ncbi.nlm.nih.gov/pubmed/21421883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6139
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