N4-aminocytidine, a nucleoside analog that has an exceptionally high mutagenic activity.
The reaction of cytidine with hydrazine to give N4-aminocytidine was greatly promoted by addition of a less-than-stoichiometric amount of bisulfite, and the product was isolated in a good yield. N4-Aminocytidine was strongly mutagenic to bacteria (Salmonella typhimurium TA100 and TA1535, and E. coli...
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| Udgivet i: | Nucleic Acids Res |
|---|---|
| Principais autores: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1983
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326252/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6224136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/11.15.5223 |
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