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What it takes to understand and cure a living system: computational systems biology and a systems biology-driven pharmacokinetics–pharmacodynamics platform

The utility of model repositories is discussed in the context of systems biology (SB). It is shown how such repositories, and in particular their live versions, can be used for computational SB: we calculate the robustness of the yeast glycolytic network with respect to perturbations of one of its e...

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Bibliografiske detaljer
Main Authors: Swat, Maciej, Kiełbasa, Szymon M., Polak, Sebastian, Olivier, Brett, Bruggeman, Frank J., Tulloch, Mark Quinton, Snoep, Jacky L., Verhoeven, Arthur J., Westerhoff, Hans V.
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262244/
https://ncbi.nlm.nih.gov/pubmed/22419971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2010.0011
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