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The amplifier effect: how Pin1 empowers mutant p53
Mutation of p53 occurs in 15 to 20% of all breast cancers, and with higher frequency in estrogen-receptor negative and high-grade tumors. Certain p53 mutations contribute to malignant transformation not only through loss of wild-type p53 but also through a gain of function of specific p53 mutations....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262197/ https://ncbi.nlm.nih.gov/pubmed/22017796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2941 |
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