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Lipopolysaccharide enhances transforming growth factor β1-induced PDGF-B expression in bile duct epithelial cells

BACKGROUND AND AIM: Platelet-derived growth factor (PDGF)-B is a potent profibrogenic mediator expressed by bile duct epithelial cells (BDECs) that contributes to liver fibrosis after bile duct ligation. However, the mechanism of PDGF-B induction in BDECs during cholestasis is not known. Transformin...

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Autors principals: Kassel, Karen M., Sullivan, Bradley P., Luyendyk, James P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262076/
https://ncbi.nlm.nih.gov/pubmed/22004089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1440-1746.2011.06941.x
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