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PET imaging of EGF receptors using [(18)F]FBEM-EGF in a Head and Neck Squamous Cell Carcinoma model

PURPOSE: To prepare and evaluate a new radiotracer for molecular imaging of cell surface receptors for epidermal growth factor (EGF). METHODS: Cys tagged EGF (cEGF) was labeled with (18)F by coupling the free thiol group of the Cys tag with N-[2-(4-[(18)F]fluorobenzamido)ethyl]maleimide ([(18)F]FBEM...

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Bibliographic Details
Main Authors: Li, Weihua, Niu, Gang, Lang, Lixin, Guo, Ning, Ma, Ying, Kiesewetter, Dale O., Backer, Joseph M., Shen, Baozhong, Chen, Xiaoyuan
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262064/
https://ncbi.nlm.nih.gov/pubmed/22109665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-011-1969-8
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