Subchronic Pulmonary Pathology, Iron Overload, and Transcriptional Activity after Libby Amphibole Exposure in Rat Models of Cardiovascular Disease

Background: Surface-available iron (Fe) is proposed to contribute to asbestos-induced toxicity through the production of reactive oxygen species. Objective: Our goal was to evaluate the hypothesis that rat models of cardiovascular disease with coexistent Fe overload would be increasingly sensitive t...

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Detalhes bibliográficos
Main Authors: Shannahan, Jonathan H., Nyska, Abraham, Cesta, Mark, Schladweiler, Mette C.J., Vallant, Beena D., Ward, William O., Ghio, Andrew J., Gavett, Stephen H., Kodavanti, Urmila P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261949/
https://ncbi.nlm.nih.gov/pubmed/21979745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1103990
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