Stem Cells Propagate Their DNA by Random Segregation in the Flatworm Macrostomum lignano

Adult stem cells are proposed to have acquired special features to prevent an accumulation of DNA-replication errors. Two such mechanisms, frequently suggested to serve this goal are cellular quiescence, and non-random segregation of DNA strands during stem cell division, a theory designated as the...

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Bibliographic Details
Main Authors: Verdoodt, Freija, Willems, Maxime, Mouton, Stijn, De Mulder, Katrien, Bert, Wim, Houthoofd, Wouter, Smith, Julian, Ladurner, Peter
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261893/
https://ncbi.nlm.nih.gov/pubmed/22276162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030227
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