Early Induction of Oxidative Stress in Mouse Model of Alzheimer Disease with Reduced Mitochondrial Superoxide Dismutase Activity

While oxidative stress has been linked to Alzheimer's disease, the underlying pathophysiological relationship is unclear. To examine this relationship, we induced oxidative stress through the genetic ablation of one copy of mitochondrial antioxidant superoxide dismutase 2 (Sod2) allele in mutan...

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Autores principales: Lee, Hyun-Pil, Pancholi, Neel, Esposito, Luke, Previll, Laura A., Wang, Xinglong, Zhu, Xiongwei, Smith, Mark A., Lee, Hyoung-gon
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261865/
https://ncbi.nlm.nih.gov/pubmed/22276093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028033
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