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A systems-based mathematical modelling framework for investigating the effect of drugs on solid tumours

BACKGROUND: Elucidating the effects of drugs on solid tumours is a highly challenging multi-level problem, since this involves many complexities associated with transport and cellular response, which in turn is characterized by highly non-linear chemical signal transduction. Appropriate systems fram...

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Autors principals: Liu, Cong, Krishnan, J, Xu, Xiao Yun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261817/
https://ncbi.nlm.nih.gov/pubmed/22152406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-8-45
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