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Effect of ΔFosB Overexpression on Opioid and Cannabinoid Receptor-Mediated Signaling in the Nucleus Accumbens
The stable transcription factor ΔFosB is induced in the nucleus accumbens (NAc) by chronic exposure to several drugs of abuse, and transgenic expression of ΔFosB in the striatum enhances the rewarding properties of morphine and cocaine. However, the mechanistic basis for these observations is incomp...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3261795/ https://ncbi.nlm.nih.gov/pubmed/21907220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.08.046 |
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