NPY and MC4R signaling regulate thyroid hormone levels during fasting through both central and peripheral pathways

Fasting-induced suppression of the hypothalamic-pituitary-thyroid (HPT) axis is an adaptive response to decrease energy expenditure during food deprivation. Previous studies demonstrate that leptin communicates nutritional status to the HPT axis through thyrotropin-releasing hormone (TRH) in the par...

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Autors principals: Vella, Kristen R., Ramadoss, Preeti, Lam, Francis S., Harris, Jamie C., Ye, Felix D., Same, Paul D., O’Neill, Nicholas F., Maratos-Flier, Eleftheria, Hollenberg, Anthony N.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261758/
https://ncbi.nlm.nih.gov/pubmed/22100407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.10.009
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