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The critical role of IRAK4-mediated NFκB activation in modified-LDL-induced atherosclerosis

BACKGROUND: Development of atherosclerosis, which is the leading cause of death in developed countries is due to persistent chronic inflammation in the artery wall. Exciting discoveries related to IL-1R-TLR signaling in development of atherosclerosis plaque have triggered intense interest in the mol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Tae Whan, Febbraio, Maria, Robinet, Peggy, DuGar, Brandon, Greene, Diane, Cerny, Anna, Latz, Eicke, Gilmour, Raymond, Staschke, Kirk, Chisolm, Guy, Fox, Paul L, DiCorleto, Paul E, Smith, Jonathan D., Li, Xiaoixa
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261755/
https://ncbi.nlm.nih.gov/pubmed/21278342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002242
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