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Lyapunov exponents and phase diagrams reveal multi-factorial control over TRAIL-induced apoptosis

Receptor-mediated apoptosis proceeds via two pathways: one requiring only a cascade of initiator and effector caspases (type I behavior) and the second requiring an initiator–effector caspase cascade and mitochondrial outer membrane permeabilization (type II behavior). Here, we investigate factors c...

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Detalhes bibliográficos
Main Authors: Aldridge, Bree B, Gaudet, Suzanne, Lauffenburger, Douglas A, Sorger, Peter K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261706/
https://ncbi.nlm.nih.gov/pubmed/22108795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.85
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