Comparison of Visual and automated assessment of Ki-67 proliferative activity and their impact on outcome in primary operable invasive ductal breast cancer

BACKGROUND: Immunohistochemistry of Ki-67 protein is widely used to assess tumour proliferation, and is an established prognostic factor in breast cancer. There is interest in automating the assessment of Ki-67 labelling index (LI) with possible benefits in handling increased workload, with improved...

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Detalhes bibliográficos
Main Authors: Mohammed, Z M A, McMillan, D C, Elsberger, B, Going, J J, Orange, C, Mallon, E, Doughty, J C, Edwards, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261670/
https://ncbi.nlm.nih.gov/pubmed/22251968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.569
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