LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

Regulation of mtDNA expression is critical for maintaining cellular energy homeostasis and may, in principle, occur at many different levels. The leucine-rich pentatricopeptide repeat containing (LRPPRC) protein regulates mitochondrial mRNA stability and an amino-acid substitution of this protein ca...

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Main Authors: Ruzzenente, Benedetta, Metodiev, Metodi D, Wredenberg, Anna, Bratic, Ana, Park, Chan Bae, Cámara, Yolanda, Milenkovic, Dusanka, Zickermann, Volker, Wibom, Rolf, Hultenby, Kjell, Erdjument-Bromage, Hediye, Tempst, Paul, Brandt, Ulrich, Stewart, James B, Gustafsson, Claes M, Larsson, Nils-Göran
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2012
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261557/
https://ncbi.nlm.nih.gov/pubmed/22045337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.392
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