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LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

Regulation of mtDNA expression is critical for maintaining cellular energy homeostasis and may, in principle, occur at many different levels. The leucine-rich pentatricopeptide repeat containing (LRPPRC) protein regulates mitochondrial mRNA stability and an amino-acid substitution of this protein ca...

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Detalhes bibliográficos
Main Authors: Ruzzenente, Benedetta, Metodiev, Metodi D, Wredenberg, Anna, Bratic, Ana, Park, Chan Bae, Cámara, Yolanda, Milenkovic, Dusanka, Zickermann, Volker, Wibom, Rolf, Hultenby, Kjell, Erdjument-Bromage, Hediye, Tempst, Paul, Brandt, Ulrich, Stewart, James B, Gustafsson, Claes M, Larsson, Nils-Göran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261557/
https://ncbi.nlm.nih.gov/pubmed/22045337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.392
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