LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

Regulation of mtDNA expression is critical for maintaining cellular energy homeostasis and may, in principle, occur at many different levels. The leucine-rich pentatricopeptide repeat containing (LRPPRC) protein regulates mitochondrial mRNA stability and an amino-acid substitution of this protein ca...

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Bibliografski detalji
Glavni autori: Ruzzenente, Benedetta, Metodiev, Metodi D, Wredenberg, Anna, Bratic, Ana, Park, Chan Bae, Cámara, Yolanda, Milenkovic, Dusanka, Zickermann, Volker, Wibom, Rolf, Hultenby, Kjell, Erdjument-Bromage, Hediye, Tempst, Paul, Brandt, Ulrich, Stewart, James B, Gustafsson, Claes M, Larsson, Nils-Göran
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261557/
https://ncbi.nlm.nih.gov/pubmed/22045337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.392
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