8-Hydroxydeoxyguanosine: Not mere biomarker for oxidative stress, but remedy for oxidative stress-implicated gastrointestinal diseases

Reactive oxygen species (ROS) attack guanine bases in DNA easily and form 8-hydroxydeoxyguanosine (8-OHdG), which can bind to thymidine rather than cytosine, based on which, the level of 8-OHdG is generally regarded as a biomarker of mutagenesis consequent to oxidative stress. For example, higher le...

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Bibliografiske detaljer
Main Authors: Ock, Chan-Young, Kim, Eun-Hee, Choi, Duck Joo, Lee, Ho Jae, Hahm, Ki-Baik, Chung, Myung Hee
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Co., Limited 2012
Fag:
Editorial
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261525/
https://ncbi.nlm.nih.gov/pubmed/22294836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i4.302
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