Ancient Pbx-Hox signatures define hundreds of vertebrate developmental enhancers

BACKGROUND: Gene regulation through cis-regulatory elements plays a crucial role in development and disease. A major aim of the post-genomic era is to be able to read the function of cis-regulatory elements through scrutiny of their DNA sequence. Whilst comparative genomics approaches have identifie...

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Bibliographic Details
Main Authors: Parker, Hugo J, Piccinelli, Paul, Sauka-Spengler, Tatjana, Bronner, Marianne, Elgar, Greg
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261376/
https://ncbi.nlm.nih.gov/pubmed/22208168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-637
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