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Synthesis and Evaluation of Novel Tc-99m Labeled Probestin Conjugates for Imaging APN/CD13 Expression In Vivo

The enzyme aminopeptidase N (APN, also known as CD13) is known to play an important role in tumor proliferation, attachment, angiogenesis, and tumor invasion. In this study, we hypothesized that a radiolabeled high affinity APN inhibitor could be potentially useful for imaging APN expression in vivo...

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Detalhes bibliográficos
Main Authors: Pathuri, Gopal, Hedrick, Andria F., Disch, Bryan, Doan, John, Ihnat, Michael A., Awasthi, Vibhudutta, Gali, Hariprasad
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261373/
https://ncbi.nlm.nih.gov/pubmed/22148582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200546b
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