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Small changes in free energy assignments for unpaired bases do not affect predicted secondary structures in single stranded RNA.

We present extensive calculations of the secondary structure of mRNA which point to its insensitivity to small changes in the free energy assignments of single stranded regions. Truncating the free energies of hairpin loops, bulges, internal loops and multibranched junctions to two significant digit...

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Detalhes bibliográficos
Main Authors: Nussinov, R, Tinoco, I, Jacobson, A B
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC326137/
https://ncbi.nlm.nih.gov/pubmed/7063404
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