ErbB2, EphrinB1, Src Kinase and PTPN13 Signaling Complex Regulates MAP Kinase Signaling in Human Cancers

In non-cancerous cells, phosphorylated proteins exist transiently, becoming de-phosphorylated by specific phosphatases that terminate propagation of signaling pathways. In cancers, compromised phosphatase activity and/or expression occur and contribute to tumor phenotype. The non-receptor phosphatas...

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Detalhes bibliográficos
Main Authors: Vermeer, Paola D., Bell, Megan, Lee, Kimberly, Vermeer, Daniel W., Wieking, Byrant G., Bilal, Erhan, Bhanot, Gyan, Drapkin, Ronny I., Ganesan, Shridar, Klingelhutz, Aloysius J., Hendriks, Wiljan J., Lee, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261204/
https://ncbi.nlm.nih.gov/pubmed/22279592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030447
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