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Circulating Angiopoietin-2 as a Biomarker in ANCA-Associated Vasculitis

The endothelial-specific Angiopoietin-Tie2 ligand-receptor system is an important regulator of endothelial activation. Binding of angiopoietin-2 (Ang-2) to Tie2 receptor renders the endothelial barrier responsive to pro-inflammatory cytokines. We previously showed that circulating Ang-2 correlated w...

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Main Authors: Monach, Paul A., Kümpers, Philipp, Lukasz, Alexander, Tomasson, Gunnar, Specks, Ulrich, Stone, John H., Cuthbertson, David, Krischer, Jeffrey, Carette, Simon, Ding, Linna, Hoffman, Gary S., Iklé, David, Kallenberg, Cees G. M., Khalidi, Nader A., Langford, Carol A., Seo, Philip, St. Clair, E. William, Spiera, Robert, Tchao, Nadia, Ytterberg, Steven R., Haubitz, Marion, Merkel, Peter A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261176/
https://ncbi.nlm.nih.gov/pubmed/22279570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030197
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