Circulating Angiopoietin-2 as a Biomarker in ANCA-Associated Vasculitis

The endothelial-specific Angiopoietin-Tie2 ligand-receptor system is an important regulator of endothelial activation. Binding of angiopoietin-2 (Ang-2) to Tie2 receptor renders the endothelial barrier responsive to pro-inflammatory cytokines. We previously showed that circulating Ang-2 correlated w...

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Hlavní autoři: Monach, Paul A., Kümpers, Philipp, Lukasz, Alexander, Tomasson, Gunnar, Specks, Ulrich, Stone, John H., Cuthbertson, David, Krischer, Jeffrey, Carette, Simon, Ding, Linna, Hoffman, Gary S., Iklé, David, Kallenberg, Cees G. M., Khalidi, Nader A., Langford, Carol A., Seo, Philip, St. Clair, E. William, Spiera, Robert, Tchao, Nadia, Ytterberg, Steven R., Haubitz, Marion, Merkel, Peter A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261176/
https://ncbi.nlm.nih.gov/pubmed/22279570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030197
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