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Genetic Signatures of Exceptional Longevity in Humans

Like most complex phenotypes, exceptional longevity is thought to reflect a combined influence of environmental (e.g., lifestyle choices, where we live) and genetic factors. To explore the genetic contribution, we undertook a genome-wide association study of exceptional longevity in 801 centenarians...

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Autores principales: Sebastiani, Paola, Solovieff, Nadia, DeWan, Andrew T., Walsh, Kyle M., Puca, Annibale, Hartley, Stephen W., Melista, Efthymia, Andersen, Stacy, Dworkis, Daniel A., Wilk, Jemma B., Myers, Richard H., Steinberg, Martin H., Montano, Monty, Baldwin, Clinton T., Hoh, Josephine, Perls, Thomas T.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261167/
https://ncbi.nlm.nih.gov/pubmed/22279548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029848
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