Consolidation of Remote Fear Memories Involves Corticotropin-Releasing Hormone (CRH) Receptor Type 1-Mediated Enhancement of AMPA Receptor GluR1 Signaling in the Dentate Gyrus

Persistent dreadful memories and hyperarousal constitute prominent psychopathological features of posttraumatic stress disorder (PTSD). Here, we used a contextual fear conditioning paradigm to demonstrate that conditional genetic deletion of corticotropin-releasing hormone (CRH) receptor 1 within th...

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Detalhes bibliográficos
Main Authors: Thoeringer, Christoph K, Henes, Kathrin, Eder, Matthias, Dahlhoff, Maik, Wurst, Wolfgang, Holsboer, Florian, Deussing, Jan M, Moosmang, Sven, Wotjak, Carsten T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260988/
https://ncbi.nlm.nih.gov/pubmed/22030710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.256
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