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NMDA Receptors, mGluR5, and Endocannabinoids are Involved in a Cascade Leading to Hippocampal Long-Term Depression

In the CA1 region of the rat hippocampus, metabotropic glutamate receptor-5 (mGluR5) and cannabinoid-1 receptors (CB1Rs) are believed to participate in long-term synaptic depression (LTD). How mGluRs and CB1Rs interact to promote LTD remains uncertain. In this study, we examined LTD induced by CB1R...

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Bibliografske podrobnosti
Main Authors: Izumi, Yukitoshi, Zorumski, Charles F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260982/
https://ncbi.nlm.nih.gov/pubmed/21993209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.243
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