GGPPS, a New EGR-1 Target Gene, Reactivates ERK 1/2 Signaling through Increasing Ras Prenylation

Cigarette smoke activates the extracellular signal-regulated kinase (ERK) 1/2 mitogen activated-protein kinase pathway, which, in turn, is responsible for early growth response gene-1 (EGR-1) activation. Here we provide evidence that EGR-1 activation can also reactivate ERK 1/2 mitogen activated-pro...

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Bibliographische Detailangaben
Hauptverfasser: Shen, Ning, Shao, Yue, Lai, Shan-Shan, Qiao, Long, Yang, Run-Lin, Xue, Bin, Pan, Fei-Yan, Chen, Hua-Qun, Li, Chao-Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2011
Schlagworte:
Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260860/
https://ncbi.nlm.nih.gov/pubmed/21983072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.08.011
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