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Snail1 Mediates Hypoxia-Induced Melanoma Progression
Tumor hypoxia is a known adverse prognostic factor, and the hypoxic dermal microenvironment participates in melanomagenesis. High levels of hypoxia inducible factor (HIF) expression in melanoma cells, particularly HIF-2α, is associated with poor prognosis. The mechanism underlying the effect of hypo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3260799/ https://ncbi.nlm.nih.gov/pubmed/21996677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.08.038 |
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