Lanean...

A/ASP/VAL allele combination of IGF1R, IRS2, and UCP2 genes is associated with better metabolic profile, preserved energy expenditure parameters, and low mortality rate in longevity

A large array of gene involved in human longevity seems to be in relationship with insulin/IGF1 pathway. However, if such genes interact each other, or with other genes, to reduce the age-related metabolic derangement and determine the long-lived phenotype has been poorly investigated. Thus, we test...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Barbieri, Michelangela, Boccardi, Virginia, Esposito, Antonietta, Papa, Michela, Vestini, Francesco, Rizzo, Maria Rosaria, Paolisso, Giuseppe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Netherlands 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260360/
https://ncbi.nlm.nih.gov/pubmed/21340542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9210-z
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