Substrate Specificity within a Family of Outer Membrane Carboxylate Channels

Many Gram-negative bacteria, including human pathogens such as Pseudomonas aeruginosa, do not have large-channel porins. This results in an outer membrane (OM) that is highly impermeable to small polar molecules, making the bacteria intrinsically resistant towards many antibiotics. In such microorga...

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Bibliografiske detaljer
Main Authors: Eren, Elif, Vijayaraghavan, Jagamya, Liu, Jiaming, Cheneke, Belete R., Touw, Debra S., Lepore, Bryan W., Indic, Mridhu, Movileanu, Liviu, van den Berg, Bert
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260308/
https://ncbi.nlm.nih.gov/pubmed/22272184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001242
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